[PSY 214] - Final Exam Guide - Everything you need to know! (70 pages long)
29 Nov 2016
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Document Summary
It is also the main neurotransmitter it plays a major role in our brain. There are at least 40 different nuclei over half of our synapses are. We can look at the pathway by applying a chemical dye to vglut2 and 1. The excitatory amino acid pathway: glutamate synapses. In cortical areas there is a co-localization of glutamate with monoamines and acetylcholine. This can account for the high concentration of glutamate in the brain. Responsible for many types of excitatory amino acids. Drugs that are eaa will also activate these receptors. L-ap4: drug that causes inhibitory effects; historically important to understand that glutamate binds to receptors. Others inhibit adenylyl cyclase and camp autoreceptors. 3 main types glutamate binds to all of these: Kainate: excitatory amino acid that is found in shellfish and see weed. Poisoning by seefood caused by domoic acid, which is a neurotoxin found in mussels. Ampa: play a role in motor coordination and brain excitation.
