Nursing HDP401- Final Exam Guide - Comprehensive Notes for the exam ( 51 pages long!)

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Both types of diabetes are increasing, esp. type 2. Insulin - produced in the pancreas by the islet of langerhans (beta cells), insulin lower blood glucose concentration. Other effects include - increased protein synthesis (need for growth/repair), increases amino acid entry into cells (need aa for protein synthesis), increased potassium entry into cells, inhibits lipolysis and increases lipogenesis. Insulin interact with other hormones esp. those that increase blood glucose (glucocorticoids, glucagon, thyroid hormones/t3 &t4), epinephrine (increases metabolic rate), growth hormone - all are antagonist of insulin which increases the need for insulin. Growth hormone is also an agonist - insulin and growth hormone go hand and hand for normal growth/development. Type 1 diabetes (juvenile onset/insulin dependant diabetes mellitus) >50, non-insulin dependant diabetes mellitus: no absolute deficiency of insulin, huge increase in all over the world - d/t more access to food and less labour/physical work being. Lack of insulin, interference with insulin, cells less receptive to insulin.

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