HSCI 338 Study Guide - Final Guide: Ebola Vaccine, Cell-Mediated Immunity, Viral Disease

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Chapters 13, 14, 15, 16, 18, 19, 20, 21, 24. Interactions between animal viruses and cells - ch 15. Immune system innate and adaptive defences - ch 13 & 14. Hsv & latency - found in ch 17 (not phage section) Emerging infections - ch 24 + supplemental articles. 2. relate animal reservoirs, ha & na variation, and mechanisms of mutation to pandemics and requirement for regular flu vaccines and current circulating strain. 3. predict how antigenic drift occurs in a lab. 4. explain how immunity within a population changes over time. 1. explain why viruses are named tumour associated viruses, not tumour virus . 2. define and distinguish between immortalisation, transformation and tumourigenesis. 3. define oncogene, proto-oncogene, and tumour suppressor: describe 3 ways that viral genes promote tumourigenesis. 5. explain why transmission of viral genes to daughter cells is important and list three ways that viral genes can be spread to daughter cells.

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