MBB 222 Study Guide - Cyclobutane, Thymine, Guanine

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Total marks for problem set = 44 marks. Problem set is due on friday, november 1st, 2013 in class. Hand in your problem set to your teaching assistant for marking in class. Answers written in pencil will not be accepted. Zero marks will be given to questions with answers that are not legible! This problem set is worth 2% towards your final mark in the course. A segment of a protein is provided below in which the r-groups specify each amino acid. The arrow is at the peptide bond between phenylalanine and serine. (1 mark) The carbon atom of the carbonyl group would form a transient covalent bond with chymotrypsin. (1 mark) P1 would involve the polypeptide segment with serine (0. 5 mark) P2 would involve polypeptide segment with alanine, aspartic acid and phenylalanine. (0. 5 mark) Answer: e (2 marks) an increase in 2,3-biphosphoglyercate leads to a greater release of oxygen from hemoglobin at the peripheral tissues.

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