ACCTG418 Midterm: qRENAL REVIEW.docx

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Hormones/ autonomic: change arteriole resistance, cells on distal tubule, sense increase flow, secretes vasoactive compound, paracrine effect, change afferent resistance, signals other jg cells. Juxtaglomerular cells: granular cells, on the wall of the afferent arteriole, secrete renin, sodium concentration in the plasma is associated with filtration, sense increase in sodium load in the tubules macula densa, messengial cells, not part of jga but are important; small pocket of juxtaglomerular cells. Na+ also renin/ angiotensin 2 for secretion peptide: anp regulates gfr and inhibits na+ reabsorb. Inhibits aldosterone: sensitive to stretch, on the sinus/ aortic arch, major veins, intrarenal (jg cells of jga, work by sensing change in blood volume, peripheral resistance, increase/ decrease b. p. (cid:224) increase/ decrease in stretch (cid:224) increase in nerve impulse frequency(cid:224) fires to med. oblongata, aldosterone, regulates reabsorption, steroid hormone from the adrenal cortex (secreted), more na+ transport protein (cid:224) more reabsorbs (cid:224) less excretion.

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