IMIN200 Final: IMIN 200 Finals Study Guide (got 90%)

• School: University of Alberta
• Department: Immunology and Infection
• Course: IMIN200
• Professor: All

Document Summary

Lecture 1: steps during an infection, exposure to pathogen, adherence to the skin or the mucosa. Lecture 2: gram negatives cell wall and periplasm (as well as inner and outer cell membranes, examples of gram . Yersinia, legionella, pseudomonas: have lipopolysaccharides as part of their outer membranes. Helps human immune system detect gram cells: some of the amino acids in the peptidoglycan layer are d-amino acids. Some are l-amino acids: gram positive thick peptidoglycan layer, examples of gram + Listeria, streptococcus, staphylococcus, bacillur antracis, bacillus subtilis, clostridium dificile: cell wall has lipotechoic acids that are common. Immune system uses this to know that it is gram : peptidoglycan = made of nag and nam. Effector of nlrs interact with the different parts of the cell to result in immune response. 2 domains effector and binding domain: nlrs can also recognize segments of lps, bacteria can change their peptidoglycan in order to avoid nod detection.