PHYSL210A Study Guide - Midterm Guide: Biliverdin, Tissue Factor, Fibrinogen

• School: University of Alberta
• Department: Physiology
• Course: PHYSL210A
• Professor: Saswati Das

Document Summary

Amphipatic: having both water loving and water fearing parts of a molecule. 7-8% of body weight in kg is blood. 55% of that blood is plasma (the liquid yellowish portion of blood), <1% is bufficoat (wbc and platelets) then 45% of blood volume is rbc. Hematopoiesis is the formation of blood cells that take place in the bone marrow. Erythropoietin (epo) that the kidneys release stimulates the marrow to make more rbc when needed. Their life span is about 120 days and is broken down for spare parts after that. If there are too many rbc then you have polycythemia and too few you have anemia. Hematocrit is the % of total blood volume occupied by packed rbc = x rbc / y total blood volume x100. Hemoglobin is made up of heme ( non-protein) + globin (protein). In a hemoglobin mcl there are 4 ferrous irons, 4 hemes and 4 globins.