[PHYSL402] - Final Exam Guide - Comprehensive Notes for the exam (136 pages long!)

• School: University of Alberta
• Department: Physiology
• Course: PHYSL402
• Professor: Dr.shamza

Document Summary

Keys to survival: energy, tissue perfusion and electrolyte balance. Human body functions as a coordinated whole: multiple organ systems communicate and cooperate to maintain homeostasis. Body maintains constant h2o content in dry, variable external enviro. In stable enviro (long ago), internal composition = identical to seawater. Problem: terrestrial organisms constantly lose internal water to surrounding air. Solution: maintain relatively stable internal enviro via homeostasis. Bathes all cells physiological controls maintain stable composition. Low tolerance to change cells of multicellular animals depend on constancy of ecf for normal function. Electrical signals intracellular and extracellular [na+], [k+], and [ca2+] If extracellular [k+] = too high depolarization contraction fibrillation (heart becomes a bag of worms and not really pumping blood) Intracellular fluid = conditioned by interstitial fluid (ecf) by plasma by organ systems it passes through. 66% total body water in intracellular fluid (28l) Noted stability of key physiological parameters: ie bp, osmolality, body temp etc: walter b. cannon.