PSYCO372 Midterm: Pscyco 372 UofA Midterm 1 Solution
Document Summary
Mc answers: b, b, a, d, a, d, c, a, b, c, c, d, b, c, a, a, d, c, c, d. Definitions: old view of genome; information travels from dna through rna to protein. One gene, one protein: proportion of phenotypic variation in a population attributable to genetic variation among individuals, logarithm of odds. Statistical test for linkage analysis; score of 3. 0+ evidence for linkage: single nucleotide polymorphism; found in at least 1% of general population. Used as genetic markers: same structure and function of genes across species, technique to make gmo with (usually temporary) reduced expression of one or more genes; genetic silencing. Short answers: qtl analysis uses molecular genetics to id multiple genes contributing to a trait. With non- human models you can induce polymorphisms to study, have greater control, different ethics, etc. Animals" results useful from subcellular level up to behaviour. Techniques: knockout, knockdown, knockin, inbred strains, crosses; all are feasible with non-humans (but not humans).
