BIOL 311 Study Guide - Midterm Guide: Transposable Element, Drug Resistance, Inverted Repeat

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Describe the generation of multiple drug-resistance plasmids. R plasmids are the main carriers of drug resistance. They acquire these genes by transposition of drug-resistance genes located between ir (inverted repeat) sequences. Once in a plasmid , the transposon carrying drug resistance can be transferred upon conjugation if it stays in the r plasmid , or it can insert into the host chromosome : question 12. As you saw in figure 15-22, the gens of multicellular eukaryotes often contain many transposable elements. Safe havens are the places for transposons insertion without negative consequences for the organism or regions of the genome where they(transposon insertions) will do minimal harm. Safe havens include duplicate genes (such as trna or rrna genes) and other transposable elements. Safe havens in bacterial genomes might be very specific sequences between genes or the repeated rrna genes: transposase protein can. B. catalyze the excision of a transposable element from a donor site.