Review – Blood and Immunity
Chapter 16 – blood - 16 pts
Chapter 24 – immune system – 17 pts
The Highlight Reel (things to focus on):
Components of blood and blood plasma
Anemia and polycythemia
Leukemia and ITP
Processes of hemostasis and coagulation
Specific vs non-specific immunity
Processes of non-specific immunity.
B-cell and T-cell reactions
Types of T- cells
Memory vs plasma cells
List 3 components of plasma.
electrolytes, proteins, fatty acids, h2o
List the 5 types of white blood cells.
lymphocytes, monocytes, neutrophils, esinophios, basophils
What do lymphocytes do?
What do megakaryocytes become?
What is the average lifespan of a red blood cell?
What components are needed for blood clotting?
What digests a clot after healing?
What is the clotting factor that converts fibrinogen into fibrin?
Which factors are usually lacking with hemophilia?
protein for clot formation
What are normal counts for RBC and WBC’s?
4.2-5.4 million rbc….5000-10000 wbc
What is polycythemia?
increased RBC What is needed for RBC production? Where does it occur?
iron, folic acid, b12, erythropoeiten… bone marrow
What is anemia?
inability of rbc to carry o2
What is deficient with pernicious anemia?
inadequate absorption of b12. needed for cell division
What is aplastic anemia?
failure of bone marrow to produce blood components
What happens to the RBC size with iron deficiency anemia?
What is the most common white blood cell?
What is the main function of erythrocytes(rbc)?
rbc's… carry o2
What is the main function of neutrophils?
eat bad stuff
What is the main function of basophils?
What is the main function of monocytes?
eat bacteria in lympph
What are the three processes involved in hemostasis?
vascular spasm, platelet plug, coagulation
What occurs with platelet plug?
exposed collagen binds and activates platelets, chemotoxins released from platelets which
attract more platelets.
What are the characteristics of the extrinsic path?
faster, shorter, less fibrin, uses thrombin,ttp
What is the limiting step of the intrinsic path?
What do platelets require to be activated?
exposed collagen bindig to it
How are the extrinsic and intrinsic pathways different?
extrinsic is faster.. extrinsic uses thrombin
What is the function of hemoglobin?
to carry o2 in rbc
Name two things secreted to limit hemostasis.
heparin, protein c, tfpi, antithrombin iii
What is hematocrit?
the ratio of rbc to plasma/wbc
What is the function of erythropoietin?
stimulates increased rbc production
Where does RBC cell removal occur? How?
spleen(has small vessels old rbcs cant fit through so theyre eaten..) liver(same??)
What occurs with leukemia?
increased prodction of immature leukocytes
What occurs with ITP? Immunity Questions
Name two functions of the immune system.
protects against pathogens, protects against foreign molecules(toxins), removes dead or