ANSC 4650 Midterm: A+ Midterm II Review Guide
3 Feb 2016
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Document Summary
C1q, attaches to the fc portion of a single igm molecule or paired igg molecules: igm is more efficient than igg for activating the complement system because its complement binding sites are closer together. C3ar and c5ar receptors can be found on mast cells, eosinophils and basophils: when these receptors bind to the anaphylatoxins c3a and c5a, these cells undergo spontaneous degranulation, in addition to fc ri, these complement receptors have been implicated in the pathogenesis of allergic reactions (i. e. asthma) because they trigger the release of vasoactive compounds (i. e. allergic reactions (i. e. asthma) because they trigger the release of vasoactive compounds (i. e. histamine) C3b and c4b and other c3 and c4 degraded products can act as opsonins once they bind to microbial surfaces and this can enhance their phagocytic clearance by phagocytic cells: c1q can act as an opsonin for apoptotic bodies.
