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BIOC 4540 (3)


10 Pages

Course Code
BIOC 4540
Rod Merrill

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NameStudent numberANSWER KEYUNIVERSITY OF GUELPHBIOC4540 ENZYMOLOGY Winter 2013 Midterm Examination February 26 2013 11301250 in CRSC 117 Instructor Prof R MerrillInstructions Time allowed80 minutesTotal marks40The exam is 9 pages and consists of 27 questionsThis midterm represents 20 of the final gradePlease write all your answers in ink if possibleNo materials may be removed from the examination roomAnswers to Part A are to marked on the computer scoring sheet see below and answers to Part B are to be written directly on this examination paperAnswers to part C are to be written in the answer booklet provided Part AOn the computer scoring sheet provided use black lead pencil to enter your sevendigit student ID number Answer Part A questions 120 on the computerscoring sheetOnly one option is correct for each of these questionsUse black lead pencilErase cleanly if you make a mistakeDo not use ink or whiteout on the computerscoring sheet Twenty 20 questions x 1 mark per question20 marks totalNo marks will be deducted for incorrect answers1The first enzyme to have its threedimensional structure determined was A alcohol dehydrogenaseB hemoglobinC RNase AD lysozymeE urease2 Phenylketonuriaiscaused by a genetic defect in A phenylalanine hydroxylase B amino acid metabolismCtyrosinehydroxylaseDaminotransferase E tetrahydrobiopterin synthesis 3 The best description of groupspecific enzymes is that theyA Show nonspecific activity against a variety of substrates B Utilize one substrate only for a single reaction C Use a variety of substrates each containing a certain functional group that is modified D Exhibit high catalytic powerE Catalyze isomerization reactions4 Enzymes can use a quantum tunneling mechanism to catalyze a reaction whenAthe G for the reaction is too high Bthe geometry of the protein is distorted so that reactant and product curves intersect Cthe temperature profile for the reaction shows a break point Dthe protein structure is not sufficiently flexibledynamic for the reactionE the lock and key mechanism fails 1
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