BIOC 4580 Study Guide - Final Guide: Multiple Drug Resistance, Chloroform, Phospholipid
4 Apr 2017
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Bioc 4580 class 32: dynamics of a membrane system of the cns- myelin and multiple sclerosis. The myelin sheath of the central nervous system, and multiple sclerosis, as examples of the intricacies of composition and communication. The central nervous system (2) is a combination of the brain (1) and the. The myelin sheath is a tight, spiral arrangement of a single membrane packed around an axon many times. Myelination in the cns is effected by oligodendrocytes and takes about 20 years. Different timespan in different species (eg. rats it takes 20 days, cows are born with myelin) The sheet finds axon (agrees to be friends4life) and extends around- lots of layers of compact myelin formed around the axon. Major dense and period lines are mixed up. Extracellular proteins and there are surface carbohydrate modifications sulfate is important. Compact myelin is a multilamellar assembly of lipids and proteins. The major proteins are mbp (myelin basic protein) & plp (proteolipid protein).
