BIOL 1080 Study Guide - Comprehensive Final Exam Guide - Time, Skeletal Muscle, Glucose
20 Nov 2018
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Document Summary
The systematic study of complex interactions in biological systems. Viewed as less mechanistic (i. e. what factor was the most important) Stimulation of fat oxidation in a muscle by the antiobesity hormone, leptin: Isolated test is done in the absence of other hormones. Different outcomes occur with reduction vs integration experiments. Vo2 max is limited mainly by cardiac output. Examining mechanisms of fatigue in an isolated, contracting muscle. Incorporates many levels from genes to proteins to tissues to integrated systems. Clinical example: type 2 diabetes and regulation of blood. Fasting blood glucose concentrations > 6. 9mm or ogtt result > 11. 1mm (@ 2hrs) Context - doesn"t tell you why blood glucose is increased. Ros can induce oxidative damage, promoting aging and disease. A certain amount of ros is protective (leads to apoptosis) Ros are a natural signal involved in adaptation (exercise training) Some studies show that vitamin c/e supplementation block mitochondrial adaptations to exercise training.
