BIOL 2400 Study Guide - Final Guide: Quantitative Genetics, Heritability, Natural Selection

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Influenced by many loci, each with small effect: experience both genetic and environmental variation, can(cid:495)t easily determine genotype & phenotype selection, understanding the genetic basis of quantitative traits allows us to predict future evolutionary responses to. Previously assumed many loci each with small effect *(infinitesimal model) Often many loci of small effect [but some loci of large effect] Loci called qtl or quantitative trait loci: qtl = chromosomal region with effect on trait. How do we determine the genetics of continuously varying traits? (1) (2) Trait variance; measure of the average magnitude of difference between each measure & the population mean. Vp= vg + ve (g is genetic and e is environmental) Vp=va+vd+vi+vm+ve ( 1 )( 2 : variances are additive they can be split in genetic and environmental sources, additive (va) summed effects of all loci (give info for evolution potential) Dominance (vd) interaction between alleles within a locus.

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