BIOL 2400 Study Guide - Midterm Guide: Allele Frequency, Effective Population Size, Genome Size

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yellowsnake384

17 May 2014

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Supplementary practice for midterm #2. [1] a diploid population consists of a1a1, a1a2 and a2a2 genotypes at a genetic locus. The frequency of the a1 allele is 0. 4 and the frequency of the a2 allele is 0. 6. Identify the process that causes lower survivorship in more inbred individuals. [3] in a haploid population, there are two genotypes a and b. The a genotype"s per capita growth rate is 2. 4 and the b genotype"s growth rate is 3. 1. [5] below is a figure that plots the relative fitness of two types of genotypes in a fruit fly species. Relative fitnesses are plotted as a function of the frequency of the sitter genotype. [7] a genetic locus in corn partially controls the spacing between leaves. Below is a table that gives average leaf spacing (in mm) for the three genotypes that occur at this locus. If leaf spacing is measured relative to the midpoint between the homozygous genotypes, then leaf spacing is.

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For the data set below, determine whether the genotypefrequencies represent a population in Hardy-WeinbergEquilibrium.(The significant digits allow you to assume you canhave an exactly representative sample of 1000 individuals. Thecritical value at probability 0.05 with (only) one degree offreedom is 3.84.) You will use a Chi-squared test and answer thequestions below.

Genotype: AA Aa aa

Frequency: 0.312 0.335 0.353

a. Let p = frequency of the "A" allele and q = the frequency ofthe "a" allele. Within a perfectly representative sample of 1000individuals, how many "A" alleles would there be?

b. Therefore, what is the value of p?

c. After finding the actual values of p and q, what are theexpected values of individuals with the genotypes AA, Aa andaa?

d. What is your Chi-squared value? e. Is this population inHardy-Weinberg equilibrium?

cyanbat514

II think this is a pretty basic Hardy-Weinberg Problem, I justdon;t know how to solve it yet. Thank you for your help!

Assume a population of 800 individuals with the followinggenotypes:452 AA, 296 Aa, and 52 aa. This is the 1stgeneration.

a. Calculate the frequencies for A___ and a___. Do this fromgenotype frequencies (do NOT assume Hardy Weinberg Equilibrium)

b. Use the allele frequencies from part a to calculate theexpected genotype frequencies for AA___ Aa___ and aa__

c. Based on your allele frequencies above, how many of eachgenotype would you expect if the population of 800 people were inHardy-Weinberg Equilibrium? AA____ Aa____aa____

d. Suppose that the original population (452 AA; 296 Aa; 52 aa)experienced an epidemic of an infectious disease that kills 75% ofeach homzygous class ( AA and aa). and 25% of the heterozygotes.How many of each genotype would survive?

e. The results of part e are still the first generation, butpost-epidemic survivors. What are the new allele frequencies?

f. Assume the 1st generation post-epidemic survivors materandomly, and there is no selection, no migration, no mutation, nogenetic drift. What frequency of each genotype is expected in the2nd generation?

g. If the 2nd generation contains 350 indivduals how many ofeach genotype do you expect?

cerisekangaroo944

Mutations can sometimes add genetic diversity to populations. Explain why new mutations in somatic (body) cells are NOT a source of genetic diversity in populations.

Why might a traight (like height in humans) show continuous variation?

Explain why most RARE recessive alles in populations are deleterious (disease-causing)?

Hair color in a new breed of goats is controlled by two alleles: A and a. Goats that have genotype AA or Aa have brown hair and goats that have genotype aa have red hair. (a) If goats that have brown hair have higher fitness than goats with red hair, what will happen to the frequency of the a allele in this population? (b) will the a allele disappear completely from the population if there is negative selection on it? Why or why not? (c) Is hair color in these goats considered a polyphenism? Why or why not?

BIOL 2400 Study Guide - Midterm Guide: Allele Frequency, Effective Population Size, Genome Size

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