BIOL 2400 Study Guide - Midterm Guide: Allele Frequency, Genotype Frequency, Population Genetics

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Population genetics the study of the genetic composition of populations and mechanisms that cause change at the genetic level over time within populations. Began applying insecticdes to coastal regions of southern france in 1969. Ester1: an allele conferring resistance to insecticide: ester1 rose to high frequency in coastal areas, spread to more distant localities from coast but is at lower frequency. Processes affecting allele frequencies in a population: natural selection, genetic drift, dispersal/migration, mutation. Studies suggest humans expanded from africa into area occupied by neanderthals. ~100,000ya and that the 2 population came in contact (interbreeding between the 2 lineages: dna evidence supports interbreeding, we have proportions of dna segments that are of neanderthal origin, evidence: Alleles with neanderthal ancestry affecting hair and skin were adaptive in humans. Hybrid incompatibilities between neanderthals and humans (reduced occurrence of neanderthal alleles affecting testes function in humans ie. genes involved in sexual function had a much lower shared percentage between neanderthals and humans)

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