BIOM 3090 Study Guide - Final Guide: Methadone, Acetaldehyde, Bronchitis

• School: University of Guelph
• Department: Biomedical Sciences
• Course: BIOM 3090
• Professor: Bettina Kalisch

Document Summary

Abused substance: administered repeatedly in pattern and amount that interferes with health or daily functioning. Main classes of abused drugs: sedatives, opioids, stimulants, hallucinogens, cannabinoids. Tolerance: reduced drug effect resulting from repeated use (higher dose required for same effect) Functional: changes in drug action ( or receptor #) Physiological: discontinued use of drug produces symptoms often opposite to effects sought by user (withdrawal) 10% in past year (1/5 use daily) Use with education, higher in males. Therapeutic approach to drug abuse: treat acute overdose (symptoms, antagonists, management of withdrawal symptoms (give drug to suppress acute withdrawal, then gradual reduction in dose, long-term rehabilitation. User seeking escape or used in pattern of alternating sedatives and stimulants. Withdrawal symptoms more common from chronic alcohol and barbiturate use (tremor, irritability, anxiety, hypertension, vomiting, sweating ) Clonidine helps with autonomic symptoms of withdrawal. Benzodiazepines can be used to treat ethanol withdrawal. Tolerance to sedative but not to respiratory depressant effect.