BIOM 3090 Study Guide - Comprehensive Final Exam Guide - Agonist, Cell Surface Receptor, Vasodilation

• School: University of Guelph
• Department: Biomedical Sciences
• Course: BIOM 3090
• Professor: Bettina Kalisch

Document Summary

Drug schedules: napra i: prescription needed for sale by pharmacist; includes prescription drugs (pr), narcotics (n) (ex. morphine), controlled substances (c1, c2, c3) and targeted substances (ts) (ex. Xanax, steroids: napra ii: prescription not required; however must be dispensed by the pharmacist behind the counter: ex. Useful drugs must have properties enabling transport from the site of administration to the target site (aka biophase) Useful drugs should be inactivated and excreted from the body at a reasonable rate to avoid duration of action concerns. Most drugs are small organic molecules that produce effects by interacting with macromolecular components of the organism called receptors. Proteins represent the most important type of receptor for drugs: some are hormones (ex. insulin, growth factors, neurotransmitters, enzymes for metabolic pathways, transporters (ex. Na+, k + atpase: structural proteins (ex. tubulin and nucleic acids) Intermolecular interactions: sum total of forces imparts high affinity of the drug for receptor.