BIOM 4070 Study Guide - Quiz Guide: Ryanodine Receptor, Extraocular Muscles, T-Tubule

• School: University of Guelph
• Department: Biomedical Sciences
• Course: BIOM 4070
• Professor: Brenda L Coomber

Document Summary

Very cellular (lots of muscle fibers, some connective tissue) Lots of actin and myosin (vey eosiniphilic) Myofilaments (actin and myosin) organized into sarcomeres. Muscle fiber (cell): composed of many parallel myofibrils. Fascicle: multiple muscle fibers bundled, compose the actual muscle. Runs z-line to z-line (made of alpha actinin) Actin anchored to z line via nebulin. I band: only actin, disappears with contraction (thin filaments slide towards middle), see in lm. H band: only myosin, disappears with contraction, see in tem. A band: (cid:271)oth, does(cid:374)"t (cid:272)ha(cid:374)ge (cid:449)ith (cid:272)o(cid:374)tra(cid:272)tio(cid:374), see in lm. M line: center of h band, connecting proteins, no change with contraction see in. Tem: z-lines get closer, when muscle contracts each sarcomere shortens as thin filaments slide, when muscle contracts each sarcomere shortens as thin filaments slide. T tubules = invaginations of sarcolemma that travel deep into muscle fibers alone the myofibrils, intersect sarcomere between a and i band. Triad: one t tubule, one pair of sr cisternae.