BIOM 4070 Study Guide - Final Guide: Common Hepatic Duct, Common Bile Duct, Bile Canaliculus
10 Dec 2016
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Document Summary
Produces hormones (endocrine) and digestive enzymes (exocrine) Covered by ct capsule; ct septa divide parenchyma (functional part) into poorly-defined lobes. Pancreatic duct empties into duodenum at hepatopancreatic ampulla. Patches of endocrine islets embedded in acini *completely separate. No duct portion secrete hormones into circulatory system. Nuclei towards basal surface, making lots of protein (enzymes), rich in rer basophilic. Eosinophilic apical surface, storing lots of protein to be secreted via exocytosis. Add sodium, bicarbonate & water to secretion. Each acinus has basal lamina supported by reticular ct, very vascular. Intercalated duct (simple cuboidal) merge with larger ducts (columnar) and eventually join pancreatic duct. Secretion stimulated by hormones (cholecystokinin & secretin) produced by enteroendocrine cells of duodenum. Won"t release zymogens unless food is present. Pancreas makes & releases enzymes in the inactive form (zymogens) so as not to digest its own tissue. Enteropeptidase (trypsin activator) is only in duodenum. Trypsin inhibitor is packaged with trypsinogen (zymogen)
