BIOM 3090 Study Guide - Final Guide: Insomnia, Constipation, Basal Ganglia
11 Sep 2017
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60 marks cardiovascular and cns pharmacology; multiple choice, matching and short answer (w/ choice) 30 marks anesthetics and pre-anesthetics; multiple choice. Acts on alpha2 receptors decrease ne in the cns decrease sns and increase psns: therefore, decrease co, adverse effects: sedation and impaired cognition (due to cns effects) Propranolol (non-selective): beta 1 = beta 2; toxicities are associated with beta 2 blockage (e. g in cases of asthma) Metoprolol (selective): beta 1 >> beta 2. Effects on bp: block beta 1 receptor in the heart decrease in cardiac output, block beta 1 receptor in the juxta-glomerular region of the kidney decrease renin release; decrease pvr. Nitroprusside: only used in emergencies; administered by iv; short acting, mechanism: dilate arterioles and venules via no (no leads to conversion of inactive myosin, toxicities: hypotension, cyanide accumulation (metabolites of drug) Verapamil: long term and emergency treatment, decrease in ca2+ relaxation vasodilation (also causes vasodilated of cardiac.
