HK 3810 Midterm: HK Unit 2 course overview

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Sensors: high pressure baroreceptors i) carotid artery - carotid sinus, wall of aorta - aortic arch. If you increase ap frequency: a) inhibit vasoconstrictor centre and cardioaccellerator centre b) stimulate cardiodecellerator centre c) hypothalamic nuclei that control adh-vp secretion: low pressure baroreceptors cardiopulmonary barorc in right atria and pulmonary artery. Projections from barorc > medulla (brain stem: cardiovascular control centre, hypothalamic nuclei to control adh-vp secretion. Arterioles > vasodilation > decrease tpr > decrease map. Map = hr (edv - esv) x tpr. Most potent regulators: neural and hormonal regulation, volume regulation, pressure (afterload) 1. clear plasma of unwanted substances: volume regulation. Cortical nephron all parts are in cortex. Juxtamedullary nephron loop of henle is in medullary space. Vasoconstrict afferent = decrease volume in glomerulus, therefore decrease volume in glomerulus (cap bed) therefore decrease pc (pg = pressure glomerulus) Vasoconstrict efferent = decrease volume out of glomerulus, therefore increase volume in glomerulus > increase pg.

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