HK 4550 Study Guide - Right Ventricular Hypertrophy, Ventricular Hypertrophy, Ubiquitin

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Inability to sustain an expected level of pressure/force production. In order to make comparisons between individuals, we measure at frc to normalize for these differences in lung volumes and inspiratory muscle lengths: record measurement of diaphragm function before and after insult. Failure if reductions in force/pressure are a result of insult and recoverable by rest. Invasive decreased lipid uptake by mitochondria, disrupted myofibrils, z-line streaming) Graph should illustrate an exponential decline from 0 ~0. 125 (< 0. 25) seconds as co2 pressure decreases from. After ~0. 125 seconds, graph should level off at. Even though the pressure gradient for co2 is small (~5mmhg), Co2 is very soluble ( solubility coefficient) allowing for rapid diffusion. P1 = p2 reaches equilibrium quickly (~0. 125 seconds) and thus is perfusion limited: lack of a specific and sensitive marker for peripheral fatigue and central failure that is clinically useful.

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