MICR 2420 : MICR2420 FULL COURSE NOTES

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Group 1 (double stranded dna): make their own dna polymerase or use hosts. Rna polymerase is that of hosts or viruses. Group 2 (single stranded dna): require host dna polymerase to make complimentary strand. Group 3 (double stranded rna): viruses contain viral dependent rna polymerase that they have packaged for instant transcription. Group 4 (+ single stranded): + strand can serve directly as mrna however requires synthesis of strand to form double stranded rna intermediate. Group 5 (- single stranded): need viral rna dependent rna polymerase to transcribe (-) into mrna (+). Group 6 (+ single strand): retroviruses that use reverse transcriptase which transcribes rna into double stranded dna which is then integrated into host genome (hiv) Group 7(double stranded dna): use reverse transcriptase. First copy dna into rna then reverse transcribe the rna into progeny. Dna using r. transcriptase found in virion. (hepatitis b virus) Some viruses envelop themselves in host membrane as a form of camo.

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