MICR 3330 Final: World of Viruses Final Exam Notes

• School: University of Guelph
• Department: Microbiology
• Course: MICR 3330
• Professor: Peter Krell

Document Summary

Topic 4: fundamentals of virus structure, diversity and replication. Icosahedral 440nm: host = acanthamoeba, 1120 genes. Pandoravirus (2003 discovered; identified as virus in 2013: shaped like greek jar, host = amoeba, 2500 genes. Range from 17nm (circovirus) to 200nm (herpesvirus) up to megavirus with diameter of. 80nm (retrovirus, cone shaped) to 450x250x250nm (entomopoxvirus, brick shaped) Nucleic acid (genome) is rna or dna. Proteins structural (virion proteins) or non structural (intracellular viral proteins) Carbohydrates glycoproteins (of envelope or capsid) or glycolipids (of envelope) Dna genomes ssdna or dsdna that range in size from 1. 3kb to 1200kb (1kb = 1000bp) Size ranges from 2, 343 bp to 31, 686 bp +ssrna. 4 conformations of rna genomes: dsrna, linear, segmented (i. e. reovirus, birnavirus, ssrna, linear, +ve sense, +rna non-segmented (i. e. picornavirus, flavivirus, +rna diploid (i. e. retrovirus, ssrna, linear, -ve sense. Rna segmented (i. e. orthomyxovirus, bunyavirus: subviral (non virus) genomes, ssrna, circular (i. e. viroids, satellites, delta agent)