NUTR 3330 Study Guide - Fall 2018, Comprehensive Midterm Notes - Protein, Metabolism, Nutrient

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12 Oct 2018
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NUTR 3330
MIDTERM EXAM
STUDY GUIDE
Fall 2018
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NUTR3330 Lecture 1
September 6, 2018
Nutrients: Macro vs. Micro
Macronutrients
Carbohydrate, protein and fat
Needed in gram amounts
Provide energy
Micronutrients
Vitamins and minerals
Needed in milli- or micro-gram amounts
Do not provide energy but facilitate energy production of macronutrients
Vitamins Discovery
Two important lines of evidence
Study of certain substances that prevent deficiency diseases
Study of accessory factors that are needed for survival of animals fed purified diets
Term coined by Polish Scientist Casimir Funk
Certain food ingredients are essential to health
“Vita” = life
“Amine” = N containing
Funk’s vitamin theory, published in 1912
Was aware the substances might later prove not all to be of an anime nature
Vitamin Definition
1. Organic Compounds
Distinct from fats, carbohydrates and proteins
2. Natural
Usually present in minute amounts
3. Essential for Normal Physiological Function
Small amount
4. Specific Deficiency Syndrome (eg. scurvy beriberi)
Caused by its absence or under-utilization
Not able to absorb or convert it
5. Not Absorbed by the host in amounts adequate to meet normal physiological needs
Vitamins: What are They?
14 Vitamins exist
B Vitamins (8 vitamins)
Thiamin (B1)
Riboflavin (B2)
Niacin (B3)
Pantothenic Acid (B5)
Pyridoxine (B6)
Biotin
Folic Acid
Cobalamin (B12)
Choline (related to B vitamins)
Vitamin C
Vitamin D
Vitamin K
Vitamin E
Vitamin A
What is Beta Carotene?
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“Pro-vitamin A
Carotenoid
Orange/yellow colour
Non-toxic; often used in multi-vitamin supplements
Vitamins: Classification
Easily classified according to solubility
Water soluble
B vitamins and Vitamin C
Dissolve in water (hydrophilic)
Cannot be stored, daily supple necessary
Move directly into blood; travel freely
Easily taken up and released by body tissues
Excess amounts excreted in urine
Fat soluble
Vitamins A, D, E & K
Cannot dissolve in water (hydrophobic)
Dissolve in fat (dietary and body)
Need dietary fat to be absorbed
Enter blood via lymph; need transport proteins
Can be stored (liver and body fat); daily supplies not as important
More concern about excess intakes
Vitamins are Organic
Organic means they contain carbon
Can be easily destroyed
Must be handled with care during storage and cooking
Especially thiamin, riboflavin, Vitamin C
Prolonged heating destroys thiamin
UV light destroys riboflavin
Oxygen destroys Vitamin C
Vitamins: Metabolic Functions
Each vitamin performs specific function
Some functions performed by one vitamin (vision and Vitamin A)
Others performed by many vitamins (antioxidants and Vitamin E, C, beta carotene)
Knowledge of normal function gives understanding of deficiency
eg. Vitamin K and blood clotting
Vitamins: General Functions
Co-enzymes: helping the enzyme; form part of physical structure and function
B Vitamins
Vitamin A, K & C
Hydrogen/Electron Acceptors/Donors
B vitamins, Vitamin C, E & K
Hormones
Vitamin D
Vitamins: 106 Years!
Nobel prizes awarded for vitamin research
The term “vitamine” was introduced in 1912 to reflect vitamin and amine for dietary factors that
could prevent diseases like beriberi, pellagra and scurvy
Today uncertainties still exist
Issues such as bioavailability, requirements for optimal health
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