PATH 3610- Final Exam Guide - Comprehensive Notes for the exam ( 41 pages long!)

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Andrew Vice

Document Summary

January 17, 2018 l5: circulatory system continued. Haemorrhage: haemorrhage occurs bc of some break in the vascular system, external haemorrhage, bleeding outside the body (including into the stomach and intestines, can be identified by looking at feces bc there will be blood in them. Into tissues: haematoma swelling of blood. Oma refers to swelling: ecchymosis ex. a bruise, like a whole bunch of petechia, petechia pinpoint haemorrhage. Hemostasis: endothelial cells of blood vessels, anticoagulant normally blood can flow past and not be stimulated to clot, procoagulant when injured, platelets, cell fragments of megakaryocytes, coagulation proteins. 12->active 12 11-> active 11, etc. has multiple steps so body can stop the process if it needs too. Prothrombin is an inactive form of thrombin, activated by enzyme xa (active factor 10) Thrombin, when activated, causes the fibrin molecules to gel together. Extrinsic body activates the most in the body.