PATH 3610 Study Guide - Final Guide: Clinical Urine Tests, Bee Sting, Sepsis
Document Summary
Changes in blood flow and body fluid balance. Oncotic pressure" thus refers to the pressure generated by this act of osmosis. You"ve probably often witnessed a similar effect yourself: with prolonged dishwashing (by hand!) or soaking in the tub, you"ll have noted that the skin of your fingers becomes wrinkled and puffy". This is because the solvent (water) has moved from the solution of lesser concentration (the dishwater or bathwater) to one of greater solute concentration, the interior of your skin cells (keratinocytes), by crossing a semipermeable membrane (the cell membranes). In most normal tissues, the tissue hydrostatic and oncotic pressures are near zero, and as such contribute little to fluid exchange. In the normal capillary, at the arteriolar end of the capillary bed vascular hydrostatic pressure (pushing fluid out of vessels) is higher than the vascular oncotic pressure (drawing fluid into vessels).