PSYC 2330 Study Guide - Final Guide: Long-Term Potentiation, Conditioned Taste Aversion, Nmda Receptor

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Published on 22 Jan 2013
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1/21/2013 4:11:00 PM
WEEK 9- MULTIPLE MEMORY SYSTEMS
when you have an experience in life, there will be various learning & memory
systems that are active at the same time.
o some will tap on certain systems more than others.
o all these learning systems will be active at the same time.
Declarative Memory System (S-S)
The amnesic patient H.M.
o In 1933, Henry M. had a bicycle accident and was unconscious for 5
min. Three years later he began to have minor seizures. By 21, he would
have 10 minor attacks per day and 1 major per week. No medication
worked.
In 1953 (Henry was 27), Dr. Scoville performed a bilateral medial
temporal lobe resection.
(epilepsy related to temporal lobe)
-if something goes wrong in temporal lobe, it spreads to
rest of the brain (is the 'beginning'). if you eliminate this
area, you could possibly reduce the spread (of seizures).
-they cut out the temporal lobe on both sides of the brain, but they
couldn’t be selective (and weren’t trying to be).
the fold of cortex removed had the HIPPOCAMPUS.
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o Seizure activity was greatly reduced, but he developed major memory loss
Anterograde Amnesia
unable to create new learning/memories
-living 'moment to moment.'
-intellect intact, see's everything as others do, but
every moment feels like a 'first awakening' and the
first experience of everything.
it was selective of where it went (only temporal lobe).
if it was results of a disease, other things would
have been affected as well such as the frontal lobe.
not him, his affect was not altered, he was aware of
memory disorder.
Observations:
- participated in social activities
- watched TV and solved crossword puzzles
- never asked for food or beverage, or to go to bed
- placid and polite
- aware of his memory disorder
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- John McDonald (video)
when confronted with the diary, refuses that he wrote in the
diary, gets very angry because he is perfectly lucid but can
not have knowledge of himself doing it.
o H.M. memory disorder was selective in five important ways
(1) Higher-order perceptual, motor, and cognitive functions not
affected
- above average IQ
- recognizes and names common objects
- normal language
(2) Loss the capacity for new learning
(Anterograde Amnesia)
-He scored 0 on tests that assess the persistence of his
memory for stories, lists of words and numbers, pictures,
or any of a large range of other material.
(3) The span of short-term memory was normal, but devastated by
delays
-could repeat series of numbers back to you, but then would
look at the instructor and have no idea who he was, and
completely forget he was learning numbers.
(4) Spared remote memory
-most remote (prior) memories were spared. Selective
problem in learning only new information.
(5) Spared other domains of learning and memory capacity
Sensory-motor learning (Star-Mirror Drawing task)
Task:
o -draw star inside a star, then only watch
yourself drawing through a mirror, and try to
draw line in between the 2 lines.
o going left makes you go right & reverse. you
see that with time people get much better.
(learning the task)
HM was able to learn the task, and was even
saving memory day to day.
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