MCIM 309 Study Guide - Final Guide: Otitis Media, Zanamivir, Cidofovir
Document Summary
Replicate in nasopharyngeal mucosal cells, symtoms by immune med(ifng, il8). Reinfected coz 4months low ab and not cross rxn with new types. Sympt-rhinorrhea, nasal cong, sore thr, pharyngeal edema. lrti in childr. : lytic in conjunctivita or pharynx epith-viremia-ab response->latent. Invade and peel urt epithelium and pneumocyte in lrt (inc chance of strep) enhancement here= pandemic. Pandemic condition= flu a, big drift or shift, h-h transm, people nonimmune. Necrosis-air trapping-hyper inflmm-collapse-x-ray light areaswe make ab for f/g-proten. Viral croup, urti, bronchiol, parotitis. treat, inhaled epinephrine, cold humid, steroids, heliox. dsdna icosahedralpapilloma: contact->replicate in basal layer-warts-cancer. No treat. herpes: large enveloped icosadeltahe, dsdna, encode dnap. Contact-> cpe, cell-cell, latency in neurons, reactivated by stress. Child=chickenpox, adults severe, immunoco-lethal, pneum, enceph. infects epith, fibro, t, neurons. Ebv: saliva, child ok, teens=mono, neoplastic in ummuno. Cmv: blood and all secretions, epith->latent in tcells-recurrence. Asympto or cytomegalic incl disease in babies, multisite symptomatic dis in unimmune. Ab can block progression, nefri bodies, pcr, imovax vaccine.