MCIM 224 Study Guide - Final Guide: Dna Virus, Papilloma, Reassortment
26 Jan 2016
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Genital herpes virus goes latent & may reactivate randomly, further spread via sexual contact during recurrences. Primary infection: newborns become infected if mother has genital hsv lesions during birth. Route of transmission is usually direct contact (e. g. touching a blister) or by inhalation of respiratory secretions. Some (herpes, varicella) are able to migrate further into the cns. Viral gene expression can be reactivated from external stimuli: stress, trauma, fever, etc. Vesicular skin llesions collect fluid from blister. Molecular pcr test for hsv 1 and hsv 2 highly sensitive & specific. Vesicular lesions: fluid filled blisters on skin . Vesicular lesions on penis/vaginal regions, flu- like symptoms: genital herpes. ^^^ genital herpes usually hsv-2 but increase of genital herpes hsv-2 in young people. Widespread skin lesions, lethargy, fever, seizures, possible death: neonatal encephalitis. Virus is easily destroyed by soap and water detergent destroys lipid envelope and removes spike glycoproteins: abreva (10, acyclovir (other cyclovir drugs):
