[MCIM 309] - Midterm Exam Guide - Comprehensive Notes for the exam (24 pages long!)

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Define characteristics used to define virus families, genera and species- genome, capsid symmetry, envelope. Family = -- viridae ex: herpesviridae: subfamily = --virinae ex: alphaherpesvirinae. Capsid symmetry: helical (influenza), icosahedral (polio), pleomorphic (irregular shape) Other ways: replication: lytic or lysogenic, physical: ph stability, thermal stability, biological: host range, serology. Double stranded= adeno and papova, polyoma, papilloma: enveloped. Double stranded= hepandna, herpes, pox: pox. Icosadeltahedral (bag like encloses, space between called tegument (contains enzymes and proteins)) , linear, larger, Rna -all negative strand rna are enveloped: positive & non-enveloped. Single stranded (icosahedral)= calici and picorna: positive & enveloped. Single stranded (icosahedral/helical) = coronoa (hel) falviv, retro and toga (icosa: negative & enveloped. Single stranded (helical)= arena, bunya, filo, orthomxo, paramyxo, rhabdo. Double stranded (icosahedral) = reo: paramyxo. Stable to: temp, acid, proteases, detergents, drying. Environmentally labile by: acid, detergents, drying and heat. Spreads in large droplets, secretions, organ transplants/transfusions. Doesn"t need to kill cell to spread.

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