MCIM 309 Study Guide - Midterm Guide: Rimantadine, Polyomaviridae, Valaciclovir

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Small pox: initiated by infection of the respiratory tract. Molluscum contagiosum: incubation period - 2 to 8 weeks. Histology: characteristic large, eosinophilic, cytoplasmic inclusions (molluscum bodies) in epithelial cells. Parvoviridae: small dna; nonenveloped icosahedral capsid. single-stranded + or sense. Biphasic disease: initial phase is related to viremia; flulike symptoms and viral shedding. B19: infectious phase: no illness or mild, flulike illness; slight decrease hemoglobin. Non-infectious phase erythema infectiosum (fifth disease); face spread to arms, legs. Children; mild exanthematous disease, adults: more severe disease with arthritis to athralgia. Transmitted in respiratory droplets and initiate infection in the respiratory tract. Fever, cough, coryza, conjunctivitus, photophobia, and typical rash; high morbidity and mortality in developing countries. Highly contagious; contagion period precedes symptoms (rash) host range: humans. Respiratory tract secretions, urine, blood, brain tissue samples. Treatment: high-dose vitamin a treatment reduces risk of measles mortality. Paramyxo- and orthomyxoviruses: cold, pharyngitis, laryngitis, tonsillitis, bronchiolitis, pneumonia.

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