PHPY 304 Final: PHPY 304 Final Study Guide

• School: U of S
• Department: Physiology and Pharmacology
• Course: PHPY 304
• Professor: Desai Kash

Document Summary

Pharmacokinetics what does the body do to the drug? (adme: drug can exist either free or bound. Bound mostly inactive: biotransformation occurs when a free drug enters any organ. Pharmacodynamics what does the drug do to the body: a drug may have side effects, almost all drugs have adverse effects due to interaction or some unknown mechanisms. Enteral involving the digestive tract: oral; sublingual; rectal. Parenteral route other than the digestive tract: generally has better absorption because it is introduced directly to the blood stream or target without having to be absorbed across the lumen. Intramuscular potentially more dangerous than subcutaneous, but absorbs better: subcutaneous safer, but more barriers to absorption than intramuscular. Drugs that are injected intravenously/intra-arterially skip the process of absorption and are therefore 100% absorbed immediately. Factors affecting absorption: characteristics of drugs that are better absorbed. Lipid-soluble: characteristics of drugs that are poorly absorbed.