BIOL130 Study Guide - Final Guide: Rechargeable Battery, Pectin, Transcriptional Regulation
Document Summary
Once a protein enters the endoplasmic reticulum, it will never reenter the cytosol. If a transfer sequence is given to the wrong protein, the protein will go to the wrong address. Synthesis of all proteins start on free ribsome. Proteins destined for mitochondria/ chloroplasts made by free ribosomes in the cytosol. Protein translocator on mitochondria and chloroplast will translocate along the outer membrane to meet with another translocator on the inner membrane so protein with appropriate signal sequence can enter the organelle. Proteins that enter er as transmembrane protein is destined to become apart of an organelle membrane. Water soluble protein will be used for lumen. Proteins glycosylated to protect protein from degradation and keep protein in er until properly folded, directs protein to proper organelle. Lysosomes are considered part of the endomembrane protein because they are formed from products synthesized by the endoplasmic reticulum and processed by the golgi apparatus.