Study Guides (248,402)
Canada (121,510)
Biology (1,112)
BIOL 302 (17)

BIOL 302 HISTOLOGY NOTES_toupload.docx

3 Pages
95 Views
Unlock Document

Department
Biology
Course
BIOL 302
Professor
Catherine Studholme
Semester
Fall

Description
BIOL 302 HISTOLOGY NOTES AARON TAI Lecture 1 – Basic Tissues - Histology – microscopical anatomy - Low magnification = looking for big structure - High magnification = looking for small structure - Membrane o Function – barrier to allow transport of molecules, energy sources, signals (molecular exchange) - Organelle – membrane bound, determines cell function - Cell membrane regulate molecular interactions o Molecular exchange for osmotic regulation o Adhesion to cell-cell and cell-matrix o Motility o Communication and signalling o Type of junctions present indicate cell function - Nucleus – genomic container (<20% = DNA), RNA synthesis, DNA replication, ribosome assembly - Nucleolus – non-membrane bound, site of ribosome assembly, active transport via pores - Mitochondria – extensive folding (cristae) = increase surface area for greater ATP production - Rough ER – translate protein on membrane - Smooth ER – synthesis, packaging, Sarcoplasmic Reticulum in muscle store Ca++, hormone synthesis - Golgi Complex – secretion, mod protein from ER (glycosalation for protection from degrade) - Peroxisome/Lysosome – degrade protein, waste, contain enzymes - Endocytosis – active process bring molecule into cell (signals, nutrients, bacteria) Lecture 2 – Epithelia I - Tissue = cells w/ same elements, in communities - Epithelia – line surface of cavities and space (lumen), 6 types o Functions – protection (abrasion resistance – keratin, mucous – goblet cells), absorption (microvilli), secretion (glands), transport (cilia), barrier (junctions) o Organization – modifiable apical surface, lateral surface and basement membrane (basal lamina), no blood vessels to prevent internal bleeding/cancer cells, held together w/ junctions  Mucous secreting cells face apical o Apical specializations  Microvilli (brush border) – increase surface area for absorption, cannot see between them, smaller than half nucleus, contrast colour to cell  Actin fiber cytoskeleton, actin core so cannot move, no basal body  Stereocilia – modified microvilli (absorption)  Very long ¾ cell  Sparse, ragged, tangled, gaps  Located in epididymis and inner ear  Cilia – transport, more than half nucleus height, gaps  Respiratory system, female reproductive tract  Microtubule cytoskeleton = axoneme (9+2 microtubule arrangement) o Tubulin = protein of microtubules  Anchor in cell = basal body = separate cell from cilia  Keratin – resist abrasion, moisture  On skin, no nuclei, tissue paper appearance, dead cells o Lateral Specializations  Adhesion Sites - Adhere through cell surface receptors  Tight junction – prevent movement of object b/w cell, most apical junction (e.g. stomach lining – keep acid in lumen) o Has transmembrane protein (occludin, claudin-1, JAM)  Adheren Junction – anchor membranes, encircle ce
More Less

Related notes for BIOL 302

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit