HLTH340 Study Guide - Drug Metabolism, Xenobiotic, Toxicokinetics
20 Dec 2013
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Discuss the 2 types of environments we have to be aware of when we"re studying environmental health. How do they relate: the two types of environment: External environment (what we normally think of): everything that is not. So our defense is things like avoidance, adrenaline, etc which on a biological level means neuroendocrine defenses, i. e. epinephrine, cortisol, etc: microbial challenges: things like hiv, sars, pandemic avian flu. These are first handled at the external membrane barrier -- skin, etc. And then inside us we have general/innate and immunity: chemical challenges: similarly to microbial challenges, there are external barriers in our body for the chemicals we encounter in the environment. Our defense is then external barriers i. e. we could breathe something into our lungs and the lungs are the barrier or even our gi tract. And then toxicological defenses, which are frequently biochemical in nature (analog of immune system for microbial challenges)
