KIN 210 Study Guide - Midterm Guide: Down Syndrome, Sister Chromatids, Edwards Syndrome

• School: University of Waterloo
• Department: Kinesiology
• Course: KIN 210
• Professor: Diane Williams

Document Summary

Cognitive impairment, problems thinking & learning, delayed language and speech. Poor muscle tone , flattened face & nose, slanted eyes, small head, ears and mouth. The number of protein-coding sequences in chromosme 21 is the smallest of any other human chromosome that is why these children survive. Dna microarrays can show upregulation of chromosome 21 genes in brain samples: trisomy 13 & trisomy 18. Most die within 1 2 months after birth: kli(cid:374)efelter(cid:859)s sy(cid:374)dro(cid:373)e xxy (cid:373)ales. Small testes, infertiliy, tall and long limbs (most common out of sex chromosomes) males: triple x syndrome xxx females. Tall, mental retardation, fertile - female: xxy sy(cid:374)dro(cid:373)e (cid:858) super (cid:373)ales(cid:859) Tall, high testosterrone levels, impulse behaviour male: tur(cid:374)er(cid:859)s sy(cid:374)dro(cid:373)e, (cid:1008)(cid:1009)x fe(cid:373)ales nonlethal monosomy. Short, webbed neck, lack prominent female secondary sexual characteristics, cogenital heart defects. Prophase : homologous chromosomes start to undergo synapsis and recombination & arrest at the dictyate stage.