KIN408 Study Guide - Midterm Guide: Central Venous Pressure, Mean Arterial Pressure, Blood Pressure
13 Mar 2018
School
Department
Course
Professor
Document Summary
Cardiac function 1: bulk of myocardium cardiomyocytes. Pressure gradient across valves determines if a valve is open or closed: diastole mitral valve is open, pressure in lv is lower than in la, lv relaxation. Systole closing of mitral valve, pressure is lv is greater than in la, lv contraction. Each of the 2 circulations of the heart has arterial (high pressure) and venous (low pressure) circulation. In pulmonic circulation: sbp/dbp = 25/10, very low as: Smaller distance the blood has to flow compared to systemic: delicate walls of alveoli may get damaged if pressure is high. Central venous pressure (cvp): venous bp in vena cava near the ra (~5 mmhg) Can create a negative pressure in lv with suction too spring-like protein) Titin helps to untwist and return to how it was before creates suction enhance filling. Steps of ec-coupling in the heart: depolarization of the sarcolemma due to the opening of the na+ channels in the membrane - systole.
