NE481 Study Guide - Final Guide: Collecting Duct System, Aldosterone, Proximal Tubule

• School: University of Waterloo
• Department: Nanotechnology Engineering
• Course: NE481
• Professor: Frank Gu

Document Summary

Drug any substance that affects the structure or functioning of an organism. Dose a specified quantity of a drug prescribed to be taken at one time or at stated intervals. Dosage administration of a therapeutic agent in prescribed amounts. Drug delivery the method or process of administering a pharmaceutical compound to achieve a therapeutic effect. Pharmacokinetics the science of the kinetics of drug absorption, distribution, and elimination. Pharmacodynamics the study of relationship between drug concentration at the site of action, and the pharmacologic response and physiological effect that influence the interaction of drug with the receptor. Typically normalized with respect to body weight or body surface area (bsa) (cid:1828)(cid:1845)(cid:1827)=((cid:1828)(cid:1849)(cid:889)(cid:882)(cid:1863)(cid:1859))(cid:2868). 7(cid:2871) (cid:883). (cid:889)3(cid:1865)(cid:2870) Invasive methods: sampling blood, spinal fluid, synovial fluid, tissue biopsy, parenteral or surgical intervention. Non-invasive: urine, saliva, feces, expired air, without parenteral or surgical intervention. Drug concentration: drug retention, transportation, results of drug dosing, drug metabolite transport. Plasma: supernatant of whole blood with anticoagulant (heparin)