FNH 250 Study Guide - Final Guide: Digestive Enzyme, Lysophospholipid Receptor, Goblet Cell

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Published on 5 Jul 2017
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Digestion
Salivary juices contain:
- Water
- Digestive enzyme salivary aylase starh → sugar
- R-factor protein necessary for vitamin B12 absorption
Chemical Secretions in Stomach
Mucous-secreting cells: Secrete an alkaline mucous; thick layer protects the stomach
wall against shear stress and acid damage
Parietal cells: Secrete HCl and intrinsic factor (vit B12 absorption)
Chief cells: secrete pepsinogen
G cells: secrete gastrin from pyloric region
Gastric juices contain:
- Water
- HCl (parietal cells)
- protein digestive enzyme, pepsin (acid-stable) (chief cells)
Pancreatic juices contain:
- water
- digestive enzymes (p. amylase, trypsin, p. lipase)
- bicarbonate (HCO3-)
Acidic chyme stimulates secretion of secretin.
P. lipase: Triglyeride → ooglyeride +  free FA
Phospholipid → lysophospholipid + FA
GIP inhibits secretion of gastric juices and slows release of stomach content into s.i.
Goblet cells found on villi produce mucous.
Crypt glands found between villi secrete intestinal juices (contain water and intestinal
digestive enzymes).
- maltase, lactase, sucrase
- Di- and Tri- peptidase (digestion small peptides)
Ileum
Terminal ileum only site for vitamin B12 absorption and bile resorption/recycling
Factors that influence time of digestion/absorption:
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Document Summary

Digestive enzyme salivary a(cid:373)ylase (cid:894)star(cid:272)h sugar(cid:895) R-factor protein necessary for vitamin b12 absorption. Mucous-secreting cells: secrete an alkaline mucous; thick layer protects the stomach wall against shear stress and acid damage. Parietal cells: secrete hcl and intrinsic factor (vit b12 absorption) G cells: secrete gastrin from pyloric region. Protein digestive enzyme, pepsin (acid-stable) (chief cells) Digestive enzymes (p. amylase, trypsin, p. lipase) Acidic chyme stimulates secretion of secretin: lipase: Gip inhibits secretion of gastric juices and slows release of stomach content into s. i. Crypt glands found between villi secrete intestinal juices (contain water and intestinal digestive enzymes). Di- and tri- peptidase (digestion small peptides) Terminal ileum only site for vitamin b12 absorption and bile resorption/recycling. Factors that influence time of digestion/absorption: fibre content fat, protein content. Bacterial synthesis of 2 vitamins vitamin k and biotin. Endocytosis (energy required) used by infants to absorb immune bodies.

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