MICB202 Pt.2 Bacterial Diseases Summary

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Department
Microbiology
Course
MICB 202
Professor
Erin Gaynor
Semester
Winter

Description
Topic 1 Introduction to Bacterial DiseasesMarch07111146 PMNomenclature of bacterial names Genusspecies with genus capitalized and entire name italicizedeg Streptococcus pyogenesPathogenicityability of an organism to cause diseasePathogen capable of causing harm to a normal host1Opportunistic pathogen harms a compromised host2Virulence measure of the pathogenicity of a microorganismCan be expressed as the cell number that will elicit a pathogenic response in the host within a given time periodMay be virulent avirulent virulence of microorganism is attributable to the possession of virulence factorsScreen clipping taken 08032011 448 PMBacterial Infectionsmay be classified asPrimary infection an initial acute infectionFactors that affect host susceptibility to infectionsSecondary infectiona second infection caused by an opportunistic Underlying diseaseinfection pathogen after primary infection has weakened the hostStressSubclinical infectionhost has no apparent symptomsPoor nutritionNosocomial infectionacquired by hospitalization AgeImmunosuppressive therapyLocal infectionrestricted to a small area of the bodyGenetics of hosts defense systemsSystemicgeneralized infection one that has spread throughout the body often caused by invasive organismsFocal infectionbegins in a restricted area and spreads throughout the body Pt2 Bacterial Diseases Page 1 Normal FloraIIMarch0811515 PMNormal florathe same bacterial species that colonize the same anatomical sites in all peopleBacteria benefit from host byHost benefits from bacteria byGnotobiotic organismsanimals that are born and bred Stable environmentMicrobial antagonism germfreeSupply of nutrientsnormal flora inhibits colonization by pathogens by occupying They haveA mode of transportadherence sites utilizing nutrients producing inhibitory byAbnormal anatomical and physiological featuresUnderdeveloped lymphatic tissues and poorly products affecting pH and available oxygenNutritional synergisms developed immune systems low antibody counts Synthesis and excretion of nutrients in excess of their ownhigher susceptibility to pathogensThin intestinal wallneeds which can be absorbed by the host eg Vitamin KSteroid metabolism organic acid production glycosidase They are removed from womb via csection and kept in reactionsgermfree environmentsStimulation of the immune system Normal flora is not required to live but it IS required to Normal flora induce antibody responses in host low leverls of live wellAB produced against normal flora natural antibodies can cross react to prevent infectioninvasion with pathogens Normal Flora ofOral CavityGastrointestinalTractRespiratory tractUrogenital tractSaliva is not a good culture mediumMostly anaerobic bacteriaNostrils contain staphylococcus epidermis and Urogenital tract is usually sterile due to urine Oral cavity is sterile at birthHelicobacter pylori is one of the only bacteria staph Aureuspassing throughLactobacillus spIs found in Bacteria grow as plaque a biofilmthat can colonize the stomach wallSinuses and lower resp tract trachea bronchi the vagina and lowers the pH to inhibit the Dental caries a result of streptococcus mutans pulmonary tissuesare usually sterilegrowth of other bacteriaproducing acidBacteria kept out by upward beating of ciliaScreen clipping taken 08032011 456 PMScreen clipping taken 08032011 457 PMScreen clipping taken 08032011 457 PMScreen clipping taken 08032011 457 PM Pt2 Bacterial Diseases Page 2
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