5. Jan 15th worksheet.pdf

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Department
Microbiology
Course
MICB 202
Professor
Tracy Kion
Semester
Winter

Description
Positive and negative selection summary of the overall process After the TCR is formed it is tested against both MHC Iand MHC II proteins displaying self peptides in the thymus interacts strongly does not interact interacts weaklywith MHCselfwith MHCselfwith MHCself peptide peptide peptide what happens what happens what happens about 50 about 50 become CD4 become CD8cellscellsrationalerationale rationale What is the key point about positive selectionWhat is the key point about negative selectionWhat is apoptosisIf a T cell passes positive and negative selection does this mean that it is guaranteed to become an effector cell ie do work in the immune system
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