HLSC 2110U Study Guide - Midterm Guide: Cholesteryl Ester, Ester, Chylomicron
23 Apr 2019
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Document Summary
Spherical macromolecular complexes of lipids and apolipoproteins or apoproteins. They differ in lipid and protein composition, site of origin, size, and density. Composed of a neutral lipid core which contains tag and cholesteryl esters surrounded by. Oriented so that the polar parts are exposed on surface making them soluble. Mucosal cell products are nascent chylomicrons which mature by addition of apo e and apo c from plasma hdl. They are carried to peripheral tissues where they are used up. In the blood, most of the particle is broken down remnant chylomicron is taken up by the liver and the apoproteins are taken up by hdl. Vldls that are produced in the liver and are used for bile synthesis and/or steroid hormone synthesis. Other vldls are secreted into the blood, modified by addition of apoproteins, become denser, and are converted to ldls and hdls. They are taken up by peripheral tissues with apoe receptors.
