ANP 1107 Study Guide - Midterm Guide: Immunoglobulin A, Immunoglobulin D, Primary Cell
Document Summary
The immune system: types of immune cells. Leukocytes (represents about 1% of total blood volume) Stem cells: hemocytoblast (same as red blood cells), become every cell type of circulation. Lymphoid lineage, committed (lymphocytes, b/t cells: the innate immune system. Ie. skin and mucous membrane, in ammation, fever, complement, interferons, natural killer cells. Margination: the process of a leukocyte adhering to the vessel wall of a capillary, rolls along the wall. Diapedesis: the movement of a leukocyte through a capillary wall. Chemotaxis: the migration of the leukocyte towards a chemical signal. A class of leukocyte that kills cells lacking the self mhc. Perforin forms pores in target cell membrane leading to osmotic lysis or granzyme-induced apoptosis. Complement system: a signalling protein cascade that leads to three main effects. Osmotic lysis of target microbe through formation of membrane attack complex. Antibody-producing cells, matter in the bone marrow, each b cell is only capable of responding to a single antigen.