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APA 2312 (3)
Midterm

apa 2312 Midterm: February 25th (Midterm Review)

by OneClass210572 , Winter 2015
2 Pages
91 Views
Winter 2015

Department
Human Kinetics
Course Code
APA 2312
Professor
Carla Geurts
Study Guide
Midterm

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Description
Review 3. Now, sodium on inside and potassium Extra office hours: Thursday Feb 26 outside. If sodium channels open up Lots of MCQ now, TMP can still be changed, but Some short answers (concepts) voltage gated channels cannot open Calculations and AP impossible. There is now a reversal of gradients. Initiate contraction: Begins with AP sent down 4. A pump needs energy. ATP to work. to motor neuron 5. Normal permeability returned. Larger neuron – larger signal Complete AP (be able to explain) Excess of sodium on outside, potassium on inside (Copy and study figure on “Complete AP” slide) Signal is brief reversal of membrane potential (-70mv - +30 mV – back to -70mV) AP Propagation Small local current (graded potentials) caused RMP: High concentration of ions on one side, by AP can help open adjacent channels low on other – gradient. Ions tend to go to lower concentrations Schwann cells insulate the axon, helps AP hop from one node of Ranvier to the next. Electrical gradient – Count positive ions inside + outside. Attracted to negative environment. AP then comes to NMJ (motor end plate) Vice versa with negative ions. Does not distinguish between type of ion Vesicles will dump AcH into pump Chemical gradient – Specific for every ion. AP travels down sarcolemma down T-tubules to Potassium ion channel leaks more than sodium be able to activate all muscle fibers at once. channel, some ions move across (move with gradient from high – low concentration) Contractile units composed of thick (myosin) & This causes a Transmembrane Potential. thin (actin) filaments Actin balls – G-actin Sodium gradient: Lots outside, few inside. String – tropomyosin, Kept in place by troponin Specific channels. Leak also, but less than Attaches to g-actin, tropomyosin, part for potassium. Causes RMP of -70mV. binding w/calcium. RMP changes sometimes. Influences from Contraction Cycle – W/ Calcium, tropo
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