BCH 4125 Study Guide - Cyclin-Dependent Kinase 1, Ubiquitin, Cycloheximide

• School: University of Ottawa
• Department: Biochemistry
• Course: BCH 4125
• Professor: Adam Rudner

Document Summary

Arrests in dna synthesis (mutant in dna synthesis) All events occur except cytokinesis, late nuclear division, early nuclear division, dna synthesis) All events occur except late nuclear division, and cytokinesis. In cdc6-delete, they skip s phase (example of mitosis with no tension) Blocks the three main processes of spindle pole duplication, initiation of dna replication, bud emergence (therefore the rest of the cell cycle) Mutant in early nuclear division (all events occur except cytokinesis, late nuclear division, early nuclear division) Codes for a part of the apc. Cdc2-ts (budding yeast): arrests as large budded cell. Cdc31 (budding yeast): arrests in mitosis, mutant in spindle pole duplication. Cdc15-ts (budding yeast): mutant in late nuclear division. Cdc3-ts (budding yeast): mutant in cytokinesis (only event that doesn t occur) Cdc7-ts (budding yeast): mutant that arrests in s phase. Cdc4-ts (budding yeast): mutant that arrests in s phase. Cdc23: codes for a part of the apc. Cdc27: codes for a part of the apc.