BIO 1140 Study Guide - Midterm Guide: Phospholipid, Cytosol, Transmembrane Protein
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6 Apr 2018
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The inner transmembrane layer is hydrophobic and lipid soluble. This allows only un-charged, non- polar and lipid soluble molecules from passing through the plasma membrane through diffusion. This limits solute diffusion and ensure selective permeability. specific to solutes such as the na/k pump which is only able to shuttle sodium and potassium across the membrane in a specific direction. This allows for selective permeability, ensuring that only needed molecules can enter or exit the cell. These proteins are: your goal is to design pharmaceutical compounds that are more efficiently transported across the membrane. Your current compound of interest cannot diffuse freely across the membrane. Provide an explanation for your answer which includes a brief description of the type of membrane protein and type of transport you choose. (4 marks) To allow the pharmaceutical to pass through the membrane, a transmembrane protein would be required.